National Systemic Lupus Erythematosus Prospective Cohort, Saudi Arabia
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- Disease Accrual damage among SLE patients in Saudi Arabia
研究概览
简要总结
SLE disease in Saudi Arabia is yet not well defined especially in a population with high consanguinity and high inbreeding coefficient . Up until now, there has been no prospective cohort study for SLE patients in Saudi Arabia. As a result, current published literature is focused on retrospective chart reviews which are subjected to many forms of bias. so the investigator proposed this prospective registry which will follow open cohort study design aiming to provide better understanding of disease presentation, course and outcomes especially if complemented by detailed immunological, molecular, genetic and microbiome data.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients defined as age greater than 18 years old.
- •Patients should fulfil one of the following classification criteria for SLE (ACR, SLICC or ACR/EULAR criteria).
- •No restriction on time of diagnosis.
排除标准
- •Patients who don't fulfil classification criteria mentioned above.
结局指标
主要结局
Disease Accrual damage among SLE patients in Saudi Arabia
时间窗: over 10 years
Mortality
次要结局
- Fetal and maternal outcomes in patients with SLE(over 5 years)
- Patient reported outcome(over 5 years)
研究者
Ibrahim Almaghlouth
Principle Investigator
King Saud University