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临床试验/NCT01774136
NCT01774136
已完成
不适用

The Effectiveness of an HIV-adapted IMCI Training and Supervision Programme of Community Caregivers to Support Interventions That Will Reduce MTCT and Improve Delivery of Other Essential Newborn and Child Survival Interventions

University of KwaZulu1 个研究点 分布在 1 个国家目标入组 1,342 人2012年4月

概览

阶段
不适用
干预措施
未指定
疾病 / 适应症
Prevention of Mother-to-child Transmission of HIV
发起方
University of KwaZulu
入组人数
1342
试验地点
1
主要终点
Prevalence of antenatal booking before 20 weeks gestation
状态
已完成
最后更新
7年前

概览

简要总结

This is a cluster randomized controlled trial (C-RCT) to evaluate the effectiveness of a Community-Integrated Management of Childhood Illness (C-IMCI) training for community caregivers (CCGs), adapted to include HIV-related interventions, on the delivery of maternal, newborn and child health interventions within households in rural communities in Ugu District, KwaZulu-Natal (KZN) Province, South Africa. The intervention includes two components: (1) a 2-week HIV/C-IMCI training for CCGs and their associated facilitators and supervisors, and (2) continuous support and supervision following the continuous quality improvement (CQI) framework, a low-technology approach to management and supervision of health programs. The primary objectives of the proposed evaluation are to measure the effect of the intervention on key outcomes, including early uptake of antenatal care, facility based delivery, postnatal visits, coverage of exclusive breastfeeding, and uptake of HIV PCR testing in infants at 6 weeks. We will also examine the effects of the intervention on immunization uptake up to 12 months and knowledge and practices of CCGs and mothers pertaining to maternal, newborn and child health.

注册库
clinicaltrials.gov
开始日期
2012年4月
结束日期
2014年4月
最后更新
7年前
研究类型
Interventional
研究设计
Parallel
性别
All

研究者

发起方
University of KwaZulu
责任方
Principal Investigator
主要研究者

Dr. Jennifer Reddy

Director

University of KwaZulu

入排标准

入选标准

  • Community caregivers
  • CCGs who work in Ugu District
  • age 18 years or older
  • with grade 9 education or greater
  • Mothers age 18 years and older who delivered a live-born infant within the prior 12 months
  • Reside in households served by participating CCGs.

排除标准

  • 未提供

结局指标

主要结局

Prevalence of antenatal booking before 20 weeks gestation

时间窗: 1 year

Prevalence of presentation for post-natal care within 7 days of delivery

时间窗: 1 year

Prevalence of exclusive breast-feeding practice at 14 weeks

时间窗: 1 year

Coverage of HIV PCR testing at 6 weeks

时间窗: 1 year

次要结局

  • Proportion of infants born to HIV-positive mothers who received ARV prophylaxis following birth (including during breastfeeding where appropriate)(1 year)
  • Knowledge and practices of mothers in the community regarding: infant feeding, HIV, availability of interventions to reduce HIV transmission, newborn care practices and recognition of serious illness in children and management of childhood illnesses(1 year)
  • Knowledge and practices of CCGs with regards to: HIV-specific interventions to improve maternal health, reduce HIV transmission and improve child survival(1 year)
  • Proportion of women who attended for antenatal care at least 4 times in pregnancy(1 year)
  • Proportion of deliveries by skilled birth attendant at a health facility(1 year)
  • Proportion of age-eligible infants who received recommended immunizations at 6, 10, and 14 weeks and 9 and 12 months(1 year)
  • Proportion of children whose growth was monitored by CCG at home(1 year)
  • Prevalence of exclusive breast-feeding practice at 6 months(1 year)
  • Proportion of women without known HIV-positive status who received HIV test in pregnancy(1 year)
  • Proportion of women without known HIV-positive status who received HIV test result in pregnancy(1 year)
  • Proportion of HIV-positive women who received CD4 test results(1 year)
  • Proportion of HIV-positive women who received ARV prophylaxis in pregnancy and during delivery(1 year)

研究点 (1)

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