The Efficacy of Olfactory Training Intervention on Olfactory and Other Non-motor Symptoms in PD

Not provided1 site in 1 country40 target enrollmentSeptember 25, 2024

ConditionsParkinson Disease Olfactory Disorder Olfactory Training

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Parkinson Disease
Sponsor: Not provided
Enrollment: 40
Locations: 1
Primary Endpoint: Olfactory Function Test
Status: Not yet recruiting
Last Updated: last year

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

To explore the efficacy of olfactory training on olfactory and other non-motor symptoms in PD.

Registry

clinicaltrials.gov

Start Date

September 25, 2024

End Date

April 10, 2025

Last Updated

last year

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Not provided

Eligibility Criteria

Inclusion Criteria

•PD was diagnosed according to the criteria of Movement Disorders and Parkinson Disease Group of Chinese Society of Neurology of Chinese Medical Association.
•Olfactory score was 1 standard deviation lower than the corresponding age norm;
•no medication plan in the past four weeks or no change in medication plan in the past four weeks, which can be maintained until the end of the experiment; 4.40-75 years old, with normal vision, hearing and language understanding and expression ability;
•5.Good cooperation of patients

Exclusion Criteria

•Parkinson\'s syndrome and Parkinson\'s plus syndrome caused by cerebrovascular disease, encephalitis, trauma, drugs, etc.;
•Neuropsychiatric diseases that may affect the sense of smell, such as depression, anxiety, schizophrenia, etc.;
•History of nasal disease or surgery, such as rhinitis, sinusitis, nasal septum deviation, etc. Upper respiratory tract infection in the past 3 weeks;
•Long-term smoking and occupations that inhale chemical irritants for a long time.

Outcomes

Primary Outcomes

Olfactory Function Test

Time Frame: baseline;15 weeks

The olfactory test developed by the Institute of Psychology, Chinese Academy of Sciences was used to evaluate the olfactory ability, including threshold, discrimination, and recognition.