Transcranial Direct Current Stimulation associated (tDCS) with Prompts for Restructuring Oral Muscle Phonetic Targets (PROMPT) in Apraxia of Speech in young people with Trisomy 21 - tDCS-PROMPT in CAS of T21: transcranial Direct Current Stimulation - Prompts for Restructuring Oral Muscle Phonetic Targets in Childhood Apraxia of Speech of Trisomy of 21

niversidade Federal do Espírito Santo0 个研究点开始时间: 2020年2月19日最近更新: 2023年5月29日

适应症

试验速览

暂无简介。

•They have to present clinical and / or genetic diagnosis of Trisomy 21 and meet criteria for intellectual disability (DSM-5) or intellectual development disorder (equivalent name found in ICD 11), and are classified according to the severity as mild (F70), moderate (F71), severe (F72), and profound (F73) according to ICD 10; they have to meet criteria for communication disorders (DSM-5), specifically speech sound disorder (F80.0); they should be clinically fit for the treatment proposed in the study and should therefore not present past or current illnesses that may be aggravated during treatment; they should also not have abnormalities in the laboratory tests, which may suggest a deterioration of their physical condition during the participation in the study; they should be able to understand the Portuguese language.

•It should not be included young people diagnosed with other associated mental disorders such as attention deficit hyperactivity disorder (ADHD), depressive and bipolar disorders, anxiety disorders, autistic spectrum disorder, stereotypic movement (with or without self-injurious behavior), impulsive disorders, and major neurocognitive disorders;
•those who have any metal in their brain or skull (splinters, fragments, pins, etc.) except for titanium, history of epilepsy, severe head injury, cochlear implant, cardiac pacemaker or intracardiac metal lines, should also not be included because of restrictions on the noninvasive brain stimulation technique; they will not be included due to MRI restrictions if they are carrying metal implant such as: heart valve, plate, pin, screw, stent, brain aneurysm clip, body shrapnel, piercing, metal prosthesis, orthodontic appliance, electronic implants such as cardiac pacemakers, neurostimulators, cochlear implants, claustrophobic patients and those with permanent makeup or tattooing done in the last three months.

发起方

niversidade Federal do Espírito Santo