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Clinical Trials/RBR-5435x9
RBR-5435x9
Not yet recruiting
Phase 2

Transcranial Direct Current Stimulation associated (tDCS) with Prompts for Restructuring Oral Muscle Phonetic Targets (PROMPT) in Apraxia of Speech in young people with Trisomy 21 - tDCS-PROMPT in CAS of T21: transcranial Direct Current Stimulation - Prompts for Restructuring Oral Muscle Phonetic Targets in Childhood Apraxia of Speech of Trisomy of 21

niversidade Federal do Espírito Santo0 sitesFebruary 19, 2020
ConditionsApraxiaR48.2

Overview

Phase
Phase 2
Intervention
Not specified
Conditions
Apraxia
Sponsor
niversidade Federal do Espírito Santo
Status
Not yet recruiting
Last Updated
2 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
February 19, 2020
End Date
TBD
Last Updated
2 years ago
Study Type
Intervention

Investigators

Sponsor
niversidade Federal do Espírito Santo

Eligibility Criteria

Inclusion Criteria

  • They have to present clinical and / or genetic diagnosis of Trisomy 21 and meet criteria for intellectual disability (DSM\-5\) or intellectual development disorder (equivalent name found in ICD 11\), and are classified according to the severity as mild (F70\), moderate (F71\), severe (F72\), and profound (F73\) according to ICD 10; they have to meet criteria for communication disorders (DSM\-5\), specifically speech sound disorder (F80\.0\); they should be clinically fit for the treatment proposed in the study and should therefore not present past or current illnesses that may be aggravated during treatment; they should also not have abnormalities in the laboratory tests, which may suggest a deterioration of their physical condition during the participation in the study; they should be able to understand the Portuguese language.

Exclusion Criteria

  • It should not be included young people diagnosed with other associated mental disorders such as attention deficit hyperactivity disorder (ADHD), depressive and bipolar disorders, anxiety disorders, autistic spectrum disorder, stereotypic movement (with or without self\-injurious behavior), impulsive disorders, and major neurocognitive disorders;
  • those who have any metal in their brain or skull (splinters, fragments, pins, etc.) except for titanium, history of epilepsy, severe head injury, cochlear implant, cardiac pacemaker or intracardiac metal lines, should also not be included because of restrictions on the noninvasive brain stimulation technique; they will not be included due to MRI restrictions if they are carrying metal implant such as: heart valve, plate, pin, screw, stent, brain aneurysm clip, body shrapnel, piercing, metal prosthesis, orthodontic appliance, electronic implants such as cardiac pacemakers, neurostimulators, cochlear implants, claustrophobic patients and those with permanent makeup or tattooing done in the last three months.

Outcomes

Primary Outcomes

Not specified

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