The Longterm Risk of Advanced Colorectal Neoplasia After Colonoscopy - A Population-based Cohort Study in Hong Kong
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 5,000
- 试验地点
- 1
- 主要终点
- Culumative incidence of advanced colorectal neoplasia
研究概览
简要总结
The primary objective of this study is to analyze the 15-year cumulative incidence of advanced colorectal neoplasia and CRC-related mortality after the index colonoscopy.
详细描述
This is a territory-wide retrospective observational cohort study using the Clinical Data Analysis and Reporting System (CDARS). We will identify patients from CDARS with colonoscopy performed from 1 January 2000 to 31 October 2020. Other relevant diagnoses, procedures, concomitant drugs, laboratory parameters and pathology results will be retrieved and studied.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •All patients with colonoscopy performed in HA hospitals during the study period would be eligible for screening.
排除标准
- •Patients with documented personal history of colorectal cancers before the study period would be excluded.
结局指标
主要结局
Culumative incidence of advanced colorectal neoplasia
时间窗: 15 years
high-risk adenomas or CRC after 15 years of index conoloscopy
次要结局
- CRC-related mortality rate(15 years)
研究者
Louis Ho Shing Lau
Resident Specialist
Chinese University of Hong Kong
