Comparison of safety, efficasy and complications of anterior versus posterior myotomy in Per Oral Endoscopic Myotomy (POEM) for treatment of Achalasia Cardia - A Randomized Double Blind Pilot Study

Asian Institute Of Gastroenterology0 个研究点目标入组 60 人开始时间: 待定最近更新: 2021年11月24日

试验速览

暂无简介。

•Achalasia cardia with Eckardt score >3 (0-12 scale achalasia) â??any type
•Treatment naÃ¯ve or history of pneumatic balloon dilatation
•Willing and able to comply with the study procedures and provide written informed consent form to participate in the study

•Previous surgery of the esophagus or stomach
•Active severe esophagitis
•Large lower esophageal diverticula
•Large > 3cm hiatal hernia
•Sigmoid esophagus
•Known gastroesophageal malignancy
•Inability to tolerate sedated upper endoscopy due to cardiopulmonary instability, severe pulmonary disease or other contraindication to endoscopy
•Cirrhosis with portal hypertension, varices, and/or ascites
•Pregnant or breastfeeding women (all women of child-bearing age will undergo urine pregnancy testing)
•Acute gastrointestinal bleeding
•Uncorrectable coagulopathy defined by INR > 1.5 or platelet < 50

发起方

Asian Institute Of Gastroenterology