Safety and Efficacy of Selegiline in Outpatient Treatment for Cocaine

National Institute on Drug Abuse (NIDA)2 个研究点分布在 1 个国家开始时间: 1995年1月最近更新: 2017年1月16日

适应症

试验速览

阶段: 2 期
状态: 已完成
发起方: National Institute on Drug Abuse (NIDA)
试验地点: 2
主要终点: Urine toxicology for cocaine

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

The purpose of this study is to evaluate the efficacy and clinical safety of selegiline in the treatment of cocaine dependence and to assess neurotoxicity (Magnetic Resonance Imaging, MRI) post-hoc as a possible variable for future stratification in clinical trials.

研究设计

研究类型: Interventional
主要目的: Treatment
盲法: Double

入排标准

年龄范围: 21 Years 至 50 Years（Adult）
性别: All
接受健康志愿者: 否

入选标准

•M/F ages 21-
•Meets DSM-IV criteria for cocaine. Agreeable to conditions of study and signed informed consent.

排除标准

•Psychiatric disorder that requires medication therapy. History of seizures. Pregnant and/or nursing women. Dependence on ETOH or benzodiazepines or other sedative/hypnotics. Acute hepatitis. Other medical conditions that deem participation to be unsafe.

结局指标

主要结局

Urine toxicology for cocaine

Self reports of cocaine and other drug use and craving

Evidence of change in neurotoxicity based on choreoathetoid movement assessments

次要结局

未报告次要终点

研究者

发起方

National Institute on Drug Abuse (NIDA)

申办方类型

Nih

研究点 (2)

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