The Effect of Curcumin Supplementation on Recovery From Exercise-induced Muscle Damage
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 36
- 主要终点
- Blood markers
研究概览
简要总结
Recent evidence suggests that curcumin supplementation may reduce muscle inflammation, oxidative markers, and muscle damage. The most favourable dosage to elicit these ergogenic effects are yet to be established; both 750mg & 1500mg has been shown to be effective. Curcumin supplementation has been ingested in numerous different ways however, no previous research to date has used curcumin in a hydrolysed (drinkable) format. The aim of this study is to investigate whether hydrolysed curcumin can reduce indices of muscle damage and improve recovery, whilst also examining a potential dose-response effect.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Inclusion criteria are as follows:
- •between the age of 18-35
- •non-smoker
- •no previous history of cardiovascular, respiratory, or neurological problems
- •not taking anticoagulant medication
- •injury-free in the 3 months prior to scheduled participation in the study
排除标准
- •Exclusion criteria include:
- •hypertension (<140/80)
- •any blood diseases or clotting issues,
- •injury, or previous injury in <3 months
结局指标
主要结局
Blood markers
时间窗: 72 hours post
Blood samples will be taken for analysis of markers of IL-6, IL-1β, TNF-α, IL-1, IL-4, IL-10 and CK will be taken
Ford and Fort
时间窗: 72 hours post
Capillary sample Ford and Fort tests
Muscle Structure
时间窗: 72 hours post
Muscle swelling - thigh girth + Ultrasound measurement
Muscle Function
时间窗: 72 hours post
maximal strength
Soreness
时间窗: 72 hours post
Perceived muscle soreness scale - Visual analouge scale
次要结局
未报告次要终点