The Effect of Curcumin Supplementation on Recovery From Exercise-induced Muscle Damage
- Conditions
- Exercise Induced Muscle Damage
- Registration Number
- NCT05346211
- Lead Sponsor
- St Mary's University College
- Brief Summary
Recent evidence suggests that curcumin supplementation may reduce muscle inflammation, oxidative markers, and muscle damage. The most favourable dosage to elicit these ergogenic effects are yet to be established; both 750mg \& 1500mg has been shown to be effective. Curcumin supplementation has been ingested in numerous different ways however, no previous research to date has used curcumin in a hydrolysed (drinkable) format. The aim of this study is to investigate whether hydrolysed curcumin can reduce indices of muscle damage and improve recovery, whilst also examining a potential dose-response effect.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 36
Inclusion criteria are as follows:
- between the age of 18-35
- non-smoker
- no previous history of cardiovascular, respiratory, or neurological problems
- not taking anticoagulant medication
- injury-free in the 3 months prior to scheduled participation in the study
Exclusion criteria include:
- hypertension (<140/80)
- any blood diseases or clotting issues,
- injury, or previous injury in <3 months
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Blood markers 72 hours post Blood samples will be taken for analysis of markers of IL-6, IL-1β, TNF-α, IL-1, IL-4, IL-10 and CK will be taken
Ford and Fort 72 hours post Capillary sample Ford and Fort tests
Muscle Structure 72 hours post Muscle swelling - thigh girth + Ultrasound measurement
Soreness 72 hours post Pressure pain threshold
Muscle Function 72 hours post Muscular endurance
- Secondary Outcome Measures
Name Time Method