Effect of Dexmedetomidine and Remimazolam on Body Temperature in Patients Undergoing Spinal Anesthesia
Not Applicable
Not yet recruiting
- Conditions
- Temperature Change, Body
- Registration Number
- NCT06853067
- Lead Sponsor
- SMG-SNU Boramae Medical Center
- Brief Summary
This study aims to evaluate the effect of dexmedetomidine and remimazolam on body temperature in patients undergoing spinal anesthesia.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 116
Inclusion Criteria
- Patients scheduled for elective surgery under spinal anesthesia
Exclusion Criteria
- Severe vascular disease
- Thyroid dysfunction
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Incidence of hypothermia Body temperature is monitored during spinal anesthesia. Incidence of temperature \<36℃ during spinal anesthesia is assessed.
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie dexmedetomidine and remimazolam's modulation of body temperature during spinal anesthesia?
How does the combination of dexmedetomidine and remimazolam compare to standard sedatives like propofol in preventing hypothermia during spinal procedures?
Which biomarkers correlate with hypothermia risk in patients administered alpha-2 adrenergic and GABA-A agonists during spinal anesthesia?
What are the incidence rates of bradycardia or respiratory depression with dexmedetomidine-remimazolam in spinal anesthesia trials?
Are there alternative sedative-anesthetic combinations targeting alpha-2 adrenergic and GABA-A receptors for hypothermia prevention in spinal surgery?