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Clinical Trials/NCT04259697
NCT04259697
Unknown
Not Applicable

Comparison of the Effects of Clinical Pilates and Whole Body Vibration Exercises on Strength, Flexibility, Balance, Bone Turnover Markers and Quality of Life in Postmenopausal Osteoporotic Women

Dokuz Eylul University1 site in 1 country34 target enrollmentJanuary 15, 2018
ConditionsOsteoporosis

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Osteoporosis
Sponsor
Dokuz Eylul University
Enrollment
34
Locations
1
Primary Endpoint
The maximum hold time on unipedal stance and on tandem stance.
Last Updated
6 years ago

Overview

Brief Summary

The aim is to compare the effects of clinical pilates and whole body vibration exercises in postmenopausal osteoporotic women on strength, flexibility, balance, bone turnover markers and quality of life.

Detailed Description

The aim of this study is to compare the effects of clinical pilates and whole body vibration exercises in postmenopausal osteoporotic women in terms of strength, flexibility, balance, bone turnover markers and quality of life. Thirty-four women who are diagnosed with postmenopausal osteoporosis will be recruited into the study. Participants will be divided into two groups: (1) clinical pilates group, (2) vibration exercises group. Exercise programs will be performed two times per week for twelve weeks. The strength of the extensor muscles of the hip, knee, back, elbow will be measured with a hand-held dynamometer. Flexibility will be assessed measuring the fingertip-to-floor distance in flexion and lateral bending. The balance performance will be assessed using the timed up and go test, Tetrax fall index and the maximum hold time on unipedal stance and on tandem stance. The short form-12 questionnaire will be used to assess the quality of life. Also, bone turnover markers will be measured. All assessments will be performed before and after exercise programs.

Registry
clinicaltrials.gov
Start Date
January 15, 2018
End Date
May 15, 2020
Last Updated
6 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Burcu Ece KORKMAZ

Principal Investigator

Dokuz Eylul University

Eligibility Criteria

Inclusion Criteria

  • Being in the postmenopausal period
  • Having body mass index equal to or greater than 18,5 kg/m²
  • A lack of regular exercise
  • Having been diagnosed with osteoporosis
  • Having the ability to walk independently

Exclusion Criteria

  • Having a cardiopulmonary problem that may prevent participating in exercise programs
  • Having kidney stones
  • Being diagnosed with diabetes
  • Presence of epilepsy
  • Having cardiological problems such as arrhythmia, using a pacemaker, hypertension
  • Having neurological disorders such as Parkinson, stroke, multiple sclerosis, neuropathy
  • Having surgery in the last 6 months

Outcomes

Primary Outcomes

The maximum hold time on unipedal stance and on tandem stance.

Time Frame: Change in the maximum hold time from baseline to twelve weeks

The maximum hold time will be calculated to assess static balance.

Plasma sclerostin concentration

Time Frame: Change in plasma sclerostin concentration from baseline to twelve weeks

Plasma sclerostin concentration will be measured to assess the process of bone resorption and formation.

Timed up and go test

Time Frame: Change in Timed up and go test from baseline to twelve weeks

Timed up and go test will be used to assess dynamic balance.

Dual-energy X-ray absorptiometry of hip and lumbar spine

Time Frame: Change in the Dual-energy X-ray absorptiometry of hip and lumbar spine from baseline to twelve weeks

Dual-energy X-ray absorptiometry of hip and lumbar spine will be measured to assess bone density.

Strength

Time Frame: Change in strength measures from baseline to twelve weeks

The strength of the extensor muscles of the hip, knee, back, elbow will be assessed with a hand-held dynamometer.

Tetrax fall index

Time Frame: Change in Tetrax fall index from baseline to twelve weeks

Tetrax fall index will be calculated to determine fall risk.

The short form-12 questionnaire

Time Frame: Change in quality of life measure from baseline to twelve weeks

The short form-12 questionnaire will be used to assess quality of life. The total score can range from 0 to 100. Lower SF-12 score indicated poorer physical and mental health.

Urinary deoxypyridinoline

Time Frame: Change in urinary deoxypyridinoline level from baseline to twelve weeks

Urinary deoxypyridinoline level will be measured to assess bone resorption.

Flexibility

Time Frame: Change in flexibility measures from baseline to twelve weeks

Flexibility wil be assessed measuring the fingertip-to-floor distance in flexion and lateral bending.

Study Sites (1)

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