Perioperative Analgesia After Knee Arthroplasty

Phase 4

• Conditions: Knee Arthroplasty
• Interventions: Procedure: Continuous femoral nerve block + periarticular infiltration; Procedure: Intraarticular and periarticular ropivacaine

• Registration Number: NCT01225484
• Lead Sponsor: Landeskrankenhaus Feldbach

Brief Summary

The purpose of this study is to compare two accepted methods of pain control in knee arthroplasty surgery.The first method combines the periarticular injection of ropivacaine with continuous blockade of the femoral nerve.The second method uses periarticular infiltration of ropivacaine in combination with an bolus of ropivacaine into an intraarticular catheter placed intraoperatively followed by a continuous intraarticular infusion of ropivacaine. All patient will also receive a sustained-release oral opioid and oral rescue opioids determined by pain severity using the Visual Analog Scale (VAS)

Detailed Description

Not available

Study Timeline

• Study Start: 2010-10
• Study First Submitted: 2010-10-19
• Study First Submitted QC: 2010-10-20
• Study First Posted: 2010-10-21
• Status Verified: 2015-04
• Last Update Submitted: 2015-04-08
• Last Update Posted: 2015-04-09
• Primary Completion: 2015-09
• Study Completion: 2015-10

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 123

Inclusion Criteria

• Elective primary knee arthroplasty
• ASA I,II,&III patients
• Spinal Anaesthesia

Exclusion Criteria

• Patients refusing consent
• Contraindications to regional anaesthesia
• Preexisting neurological disease
• Alcohol or drug abuse
• Inability to use the outcome assessment tools
• Wheel chair or walker dependent
• Pregnancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
CFNB, periarticular infiltration	Continuous femoral nerve block + periarticular infiltration	-
Intraarticular catheter, periarticular infiltration	Continuous femoral nerve block + periarticular infiltration	-
Intraarticular catheter, periarticular infiltration	Intraarticular and periarticular ropivacaine	-

Primary Outcome Measures

Name	Time	Method
Static and dynamic pain scores (VAS)	72 h

Secondary Outcome Measures

Name	Time	Method
Maximum knee flexion (active/passive)>= 90°	72 h

Trial Locations

Locations (1)

LKH Feldbach; 🇦🇹 Feldbach, Austria