uclear Nutrition Techniques and Clinical Outcomes for Childhood Cancer in Malaysia: A Prospective Study

• Conditions: Anthropometry, body composition, dietary intake, physical activity, energy expenditure, quality of life and clinical outcomes in paediatric cancer patients undergoing treatment and after treatment; Anthropometry; Body composition; Physical activity; Energy expenditure; Quality of life; Clinical outcomes; Chemotherapy; Cancer; Paediatric

• Registration Number: TCTR20220323003
• Lead Sponsor: ATIONAL UNIVERSITY OF MALAYSIA

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-03-23
• Last Update Posted: 19 August 2024
• Study Completion: 2027-01-25

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: All
• Target Recruitment: 181

Inclusion Criteria

Part I study will recruit a total of 61 paediatric leukaemia survivor from previous patients who participated in a doctoral thesis project conducted from the year 2009 to 2011 (Tan et al. 2013a; Tan et al. 2013b) as well as paediatric leukaemia survivors not involved in the doctoral study, who were previously diagnosed with ALL or AML at Hospital Tunku Azizah (HTA), Hospital Kuala Lumpur during childhood or adolescence and will have their follow-up visits.
Part II study will recruit new patients who are diagnosed with paediatric cancer aged 2.00 to 15.99 years and survive more than 3 months post-diagnosis and have sufficient general condition (Lansky score with at least 50 for patients aged below 16 years) (Lansky et al. 1987).
References:
Tan, S. Y., Poh, B. K., Chong, H. X., Ismail, M. N., Rahman, J., Zarina, A. L., Juraida, A. R. E., Tahir, A., Ruzita, A. T. and Roslee, R. 2013a. Physical activity of pediatric patients with acute leukemia undergoing induction or consolidation chemotherapy. Leukemia Research 37(1): 14-20.
Tan, S., Poh, B. K., Nadrah, M., Jannah, N., Rahman, J. and Ismail, M. 2013b. Nutritional status and dietary intake of children with acute leukemia during induction or consolidation chemotherapy. Journal of Human Nutrition and Dietetics 26: 23-33.
Lansky, S. B., List, M. A., Lansky, L. L., Ritter-Sterr, C. and Miller, D. R. 1987. The measurement of performance in childhood cancer patients. Cancer 60(7): 1651-1656.

Exclusion Criteria

1. Patients who require a transplant of bone marrow
2. Concurrent illness, such as diabetes, HIV, TB, hormonal problems, and thyroid disease
3. Children with Down syndrome, neurological developmental disabilities before diagnosis that caused patients cannot cooperate in this study
4. Experiencing any form of fever or sepsis

Study & Design

• Study Type: Observational
• Study Design: Not specified