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Clinical Trials/NCT04154449
NCT04154449
Unknown
Not Applicable

Effect of Intranasal Insulin on Postoperative Cognitive Dysfunction in Middle Aged Patients Undergoing Non Cadiac Surgery.

Minia University2 sites in 1 country57 target enrollmentFebruary 25, 2019
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ConditionsMiddle Aged Patients
InterventionsIntranasal insulin
DrugsIntranasal insulin

Overview

Phase
Not Applicable
Intervention
Intranasal insulin
Conditions
Middle Aged Patients
Sponsor
Minia University
Enrollment
57
Locations
2
Primary Endpoint
Cognitive dysfunction
Last Updated
6 years ago
OverviewInvestigatorsEligibility CriteriaArms & InterventionsOutcomesSitesSimilar Trials

Overview

Brief Summary

Our study is designed to evaluate the effect of intranasal insulin on postoperative cognitive dysfunction.

Primary outcome:

  1. The occurrence of cognitive dysfunction at approximately 7 days after surgery.

Secondary outcome:

  1. Incidence of any side effect.
Registry
clinicaltrials.gov
Start Date
February 25, 2019
End Date
December 25, 2019
Last Updated
6 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Minia University
Responsible Party
Principal Investigator
Principal Investigator

Nourhan mohamed anter

Resident of anesthesia and Intensive care

Minia University

Eligibility Criteria

Inclusion Criteria

  • •Age 40 - 60 years.
  • •Both gender.
  • •Patients will be scheduled for elective major abdominal, thoracic, orthopedic, open gynecological, open urological, spine, otolaryngological surgeries under general anesthesia with expected hospital stay \>4 days.

Exclusion Criteria

  • •Drug allergy.
  • •Patients with major psychiatric disease.
  • •Patients receive major tranquillizers and antidepressant.
  • •Those undergoing neurosurgery or cardiac surgery.
  • •Those unable or unwilling to abide by the study procedure
  • •Those who could not follow procedure or who had poor comprehension of dutch language.
  • •Those with sever visual and auditory disorder / handicaps.

Arms & Interventions

Surgical group Received intranasal insulin.

Intervention: Intranasal insulin

Outcomes

Primary Outcomes

Cognitive dysfunction

Time Frame: 7 days

The occurrence of cognitive dysfunction at approximately 7 days after surgery.

Study Sites (2)

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