Risk factors for non-melanoma skin cancer (NMSC) 1. Skin carcinoma progression analyzed by genome-wide gene expression profiling and mimicked by validated organotypic in vitro human skin cancer models; towards an integrative system-biology approach and an in vitro screening method for targeted skin cancer therapies. 2.Genetic and environmental risk factors for the development of skin cancer in organ-transplant recipients.
Recruiting
- Conditions
- skin cancersquamous cell carcinoma10040900
- Registration Number
- NL-OMON30521
- Lead Sponsor
- eids Universitair Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 1500
Inclusion Criteria
Organ-transplant patients and immunocompetent persons with and without skin cancer.
Exclusion Criteria
No consent of the patient.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What genomic biomarkers are associated with NMSC progression in organotypic in vitro models from NL-OMON30521?
How do immunosuppressive agents in transplant recipients influence NMSC risk as studied in genome-wide profiling?
Which molecular pathways are targeted by organotypic skin cancer models to mimic squamous cell carcinoma development?
What adverse events are linked to genetic-environmental interactions in NMSC among organ-transplant patients?
How does the in vitro screening method from NL-OMON30521 compare to existing models for targeted NMSC therapies?