Study on the influence of different sperm preparation methods on the ICSI outcomes of patients with high sperm DNA fragmentation rate: a randomized sibling oocyte study
Not Applicable
Completed
- Conditions
- infertility
- Registration Number
- ChiCTR2300077206
- Lead Sponsor
- the First Affiliated Hospital of Kunming Medical University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- Autologous sperm and oocyte; <br>2. First cycle; <br>3. Sperm DFI > 30%;<br>4. The woman's age is less than 38 years old.<br>
Exclusion Criteria
- Patients undergoing pre-implantation embryo genetic testing (PGT); <br>2. Excluding common male infertility factors such as karyotype abnormalities, AZF microdeletions, orchitis, epididymitis, varicocele, history of reproductive system surgery, history of mumps, sexually transmitted diseases such as syphilis and AIDS; <br>3. Testicular sperm or frozen-thawed sperm; <br>4. The number of Retrieved oocytes < 10.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method High-quality embryo rate;blastocyst formation rate;
- Secondary Outcome Measures
Name Time Method sperm DNA fragmentation rate;sperm recovery rate;fertilization rate;PR after preparation;