Myeloid cell reprogramming in thyroid carcinoma
- Conditions
- Thyroid carcinoma
- Registration Number
- NL-OMON21311
- Lead Sponsor
- Radboudumc
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Other
- Sex
- Not specified
- Target Recruitment
- 50
Inclusion Criteria
In order to be eligible to participate in this study, a subject must meet all of the following criteria:
In general: Subjects should be at least 18 years old and mentally competent
Exclusion Criteria
A potential subject who meets any of the following criteria will be excluded from participation in this study:
-Mentally incompetent
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Transcriptional and epigenetic signature and function of TAMs, BM myeloid progenitors and circulating macrophages before and after treatment.
- Secondary Outcome Measures
Name Time Method Presence of circulating tumor cells (CTC) and changes in circulating metabolites (either tumor-derived or tumor-induced) concentrations (metabolomics) associated with the functional reprogramming of the immune cells.