Assessing Reproductive Outcomes in Young Female Cancer Survivors Through a National Fertility Preservation Registry

Active, not recruiting

• Conditions: Cancer; Infertilty

• Registration Number: NCT01843140
• Lead Sponsor: University of California, San Diego

Brief Summary

The FIRST project is a national fertility preservation registry for young women facing cancer treatments. The investigators will examine how different cancers and treatments affect the reproductive health of young survivors. This prospective cohort study seeks to recruit young women close to time of cancer diagnosis and treatment. Participants will answer a yearly questionnaire on their current health. A subset of participants will provide dried blood spots to measure reproductive hormones. The primary goal of the study is to determine the risk of infertility and time to pregnancy in young female cancer survivors.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-05
• Study First Submitted: 2012-07-26
• Study First Submitted QC: 2013-04-25
• Study First Posted: 2013-04-30
• Status Verified: 2024-10
• Last Update Submitted: 2024-10-27
• Last Update Posted: 2024-10-30
• Primary Completion: 2028-04-01
• Study Completion: 2028-04-01

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: Female
• Target Recruitment: 55

Inclusion Criteria

• Diagnosed with cancer or exposure to cancer treatment
• English speaking
• Ability to consent to the study

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Risk of infertility	Annually up to 10 years	Participants will be assessed for infertility on average each year from age 18 to 51, the age of natural menopause.

Secondary Outcome Measures

Name	Time	Method
Time to pregnancy	Annually up to 10 years

Trial Locations

Locations (1)

UCSD Moores Cancer Center; 🇺🇸 La Jolla, California, United States