Ultrasound Guided Erector Spinae Plane Block Versus Quadratus Lumborum Block in Laparoscopic Cholecystectomy

Not Applicable

• Conditions: Postoperative Analgesia; Erector Spinae Plane Block; Laparoscopic Cholecystectomy; Quadratus Lumborum Block
• Interventions: Procedure: Erector spinae plane block group; Other: Control group; Procedure: Quadratus lumborum block group

• Registration Number: NCT04845711
• Lead Sponsor: Tanta University

Brief Summary

The aim of this study is to compare between the efficacy of ultrasound guided erector spinae plane block and ultrasound guided quadratus lumborum block in managing acute postoperative pain in patients undergoing laparoscopic cholecystectomy.

Detailed Description

Not available

Study Timeline

• Status Verified: 2021-04
• Study First Submitted: 2021-04-11
• Study First Submitted QC: 2021-04-11
• Last Update Submitted: 2021-04-11
• Study First Posted: 2021-04-15
• Last Update Posted: 2021-04-15
• Study Start: 2021-05-01
• Primary Completion: 2021-10-31
• Study Completion: 2021-11-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• aged 21-65 years
• both genders
• American Society of Anesthesiology (ASA) class I-II
• Undergoing elective laparoscopic cholecystectomy

Exclusion Criteria

• Patient refusal.
• Coagulopathy.
• History of allergy to local anaesthetic.
• History of liver or renal pathology affecting drug elimination
• Mental dysfunction or cognitive disorders.
• Use of medication such as gabapentin-pregabalin that could affect pain perception.
• Body Mass Index > 40 kg/m2.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Erector spinae plane block group	Erector spinae plane block group	patients will receive general anesthesia and bilateral ultrasound guided erector spinae plane block (20ml Bupivacaine 0.25%)
Control group	Control group	patients will receive general anesthesia only.
Quadratus lumborum block group	Quadratus lumborum block group	patients will receive general anesthesia and bilateral ultrasound guided quadratus lumborum block (20 ml Bupivacaine 0.25%)

Primary Outcome Measures

Name	Time	Method
The degree of postoperative pain in the first 24 hours post-operative	first 24 hours post-operative	Postoperative pain will be assessed by the numerical rating scale (NRS); 0 no pain while 10 is the maximum pain) after discharge to the ward ,and at 6, 12, 18, 24 hours.

Secondary Outcome Measures

Name	Time	Method
Time to first analgesic requirement	first 24 hours post-operative	Intravenous morphine 2 mg will be given when the numerical rating scale (NRS) equal or above 4
Total dose of intraoperative consumption of fentanyl	intraoperative	Fentanyl 0.5 μg/kg will be given if there was increase in heart rate or mean arterial blood pressure more than 20% (after exclusion of other causes than pain).
Total dose of rescue analgesia in the first 24hr postoperative	first 24 hours post-operative	Total morphine consumption 24 hours after surgery will be recorded. Intravenous morphine 2 mg will be given when the numerical rating scale (NRS) equal or above 4