Effect of serteraline in depressed aggressive patients

Phase 2

• Conditions: Depression.; Depression NOS

• Registration Number: IRCT201411122999N4
• Lead Sponsor: Tabriz University Of Medical Science

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Depression should be confirmed by a psychologist throughout a structured interview based on DSM-IV criteria; Patient should be at 1st episode of disease, with no history of anti-depression treatment (medical or non-medical); Presence of aggressive behaviors confirmed by history or medical examination; Patient prefers taking more efficient drug, no matter how expensive; Iranian nationality; Age between 20 to 40 years old; Agreement for participating in study through signing testimonial form
Exclusion criteria:
History of any psychological disease, except for depression; Present history of any drug affecting CNS/PNS; History of any of these conditions: Amyloidosis, Acute porphyria, Cardiovascular/Respiratory/Endocrine/Neurologic disease, Alcohol/drug abuse, Malabsortion, Multiple sclerosis, ALS; Pre-menstural syndrome for female; Presence of genetical susceptibility to above mentioned conditions

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Depression intensity. Timepoint: 1.5. Method of measurement: Beck Questionnaire, 2nd edition.;Anger status. Timepoint: 1.5. Method of measurement: STAXI Questionnaire, 2nd edition.;Heart rate variability. Timepoint: 1.5. Method of measurement: Biofeedback system.;Respiratory Rate. Timepoint: 1.5. Method of measurement: Biofeedback system.;Heart rate. Timepoint: 1.5. Method of measurement: Biofeedback system.;Skin Temprature. Timepoint: 1.5. Method of measurement: Biofeedback system.;Blood Pressure. Timepoint: 1.5. Method of measurement: Biofeedback system.;Valsalva Ratio. Timepoint: 1.5. Method of measurement: Biofeedback system.;Expiratory:Inspiratory ratio. Timepoint: 1.5. Method of measurement: Biofeedback system.;Skin conductivity level. Timepoint: 1.5. Method of measurement: Biofeedback system.