The Comparison of Diagnostic Yield Between Routine Computed Tomography and Colonoscope in Detecting Colorectal Tumors in Patients Who at Risk of Colorectal Cancer
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 241
- 试验地点
- 1
- 主要终点
- Diagnostic yield in diagnosis colorectal tumor
研究概览
简要总结
Colonoscopy is the mainstay modality of choice in colorectal cancer screening worldwide. However, the rate of colonoscopy for colorectal cancer screening is very low (approximately 5-10%) because of the limited local medical resources (such as endoscopists and regional endoscope). This observational diagnostic test study aims to compare the diagnostic yield of routine computed tomography and colonoscopy in detecting colorectal tumors in patients at risk of colorectal cancer (aged more than 50 years and FIT+). The main question[s] it aims to answer are:
- To compare the diagnostic yield between the routine computed tomography and colonoscopy.
- To compare the procedure-related adverse events between the routine computed tomography and colonoscopy.
详细描述
All enrolled patients underwent routine CT scans of whole abdomen, then subsequently under went a colonoscopy on the next day
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 50 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Normal platelet count and normal result of PT, PTT
排除标准
- •pregnancy or lactation
- •uncontrolled Diabetes Mellitus, hypertension, asthma, congestive heart failure
- •recent coronary artery disease within 3 months
- •eGFR lesser than 30 mL/min/1.73m2
- •hemophilia or uncontrolled or uncorrected coagulopathy
结局指标
主要结局
Diagnostic yield in diagnosis colorectal tumor
时间窗: 2 weeks
Sensitivity, specitivity, accuracy
次要结局
- Procedure-related adverse events(2 weeks)
研究者
Arunchai Chang
Head of Division of Gastroenterology, Department of Internal Medicine, Hatyai Hospital
Hat Yai Medical Education Center