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临床试验/CTRI/2025/10/096294
CTRI/2025/10/096294
尚未招募
不适用

Antiplaque efficacy of herbal based mouthwash with a novel resveratrol-based mouthwash. A Randomized clinical trial

Sudhir Rama Varma1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2025年11月3日最近更新:

概览

阶段
不适用
状态
尚未招募
发起方
Sudhir Rama Varma
入组人数
60
试验地点
1
主要终点
Dental Plaque

概览

简要总结

Mouthwashes are used by an estimated 80% of the world’s population for primary health care. They have gained popularity as a dietary supplement

for illness prevention and as an alternative/complementary therapy in recent years. Mouthwashes come in a wide variety of forms and can be found on the market all over the world.

Detailed Description: Mouthwashes have been increasingly popular over time. Ethnomedicines are the term used to describe them. Various substances have been tested, with phytopharmacological analyses yielding contradictory results. Many previous studies had tested the antiplaque efficiency of one herbal mouthwash with contradicting results, other studies have tested the Antiplaque efficiency of chlorhexidine, tea tree oil and Miswak, some studies had given positive outcomes and benefits of Miswak on the gingiva and others when comparing between the efficacy of Miswak over chlorhexidine mouth wash in dental practice provided results favouring both these mouthwashes.

In our proposed study we will compare the antiplaque efficiency of three mouthwashes, Eucalyptus, tea tree oil and Resveratrol mouthwash. Plaque and gingival bleeding scores will be taken before the study from 6 different teeth and retaken after 2 weeks and four weeks respectively the use of the mouthwash. This study is single-blinded. Antiplaque and gingival bleeding scores from the three mouthwashes will be recorded over a period of a month and statistical analysis will be performed

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
Participant Blinded

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Patients who are medically fit
  • Patients with gingival inflammation not progressed into periodontitis
  • Patients between the age of 18-60 years.

排除标准

  • Patients who are medically compromised
  • Patient who have undergone a periodontal therapy for the past 3 months
  • Patients who are healthy but have been using herbal mouthwashes.

结局指标

主要结局

Dental Plaque

时间窗: From Baseline to preintervention to the end of treatment at 4 weeks

次要结局

  • Gingival Bleeding score(From Baseline to preintervention to the end of treatment at 4 weeks)

研究者

发起方
Sudhir Rama Varma
申办方类型
Other [Self funded]
责任方
Principal Investigator
主要研究者

Sudhir Rama Varma

Ajman University

研究点 (1)

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