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Clinical Trials/NL-OMON49007
NL-OMON49007
Recruiting
Not Applicable

REvascularization versus optimal medical therapy on left Ventricular ISchemia reduction: Exploring the associations between ischemia, functional outcome and collaterals in the treatment of Chronic Total Occlusion patients - REVISE-CTO

Academisch Medisch Centrum0 sites82 target enrollmentTBD

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Not specified
Sponsor
Academisch Medisch Centrum
Enrollment
82
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
2 years ago
Study Type
Interventional

Investigators

Eligibility Criteria

Inclusion Criteria

  • 1\. A chronic total occlusion is present and target lesion. A CTO is required to
  • meet the following characteristics:
  • A 100% luminal narrowing of the coronary artery without antegrade flow, i.e.
  • Thrombolysis in Myocardial Infarction flow grade 0 or 1;
  • Older than 3 months, established with previous PCI or with angiographic
  • characteristics;
  • Amenable to percutaneous revascularization.
  • 2\. Patient has a clinical indication to perform CTO PCI.
  • 3\. A SPECT is performed at baseline to assess ischemia and a cardiac magnetic
  • resonance imaging (CMR) scan to assess viability, as part of routine patient

Exclusion Criteria

  • Subject is younger than 18 years of age;
  • Persistent or permanent atrial fibrillation;
  • Presence of a non\-MRI compatible cardiac device, i.e. pacemaker or
  • implantable cardioverter defibrillator;
  • Body weight \> 250 kg;
  • Unable to exert, i.e. due to physical disability;
  • Any contraindication for SPECT or CMR, i.e. cerebrovascular clips,
  • claustrophobia;
  • Known renal insufficiency (estimated Glomerular Filtration Rate \[eGFR] \<60
  • mL/min/1\.73m2 or serum creatinine level of \>2\.5 mg/dL or subject on dialysis);

Outcomes

Primary Outcomes

Not specified

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