Clinical trial to study the effect of modulating blood flow to liver graft in cases of portal hyperperfusion in living donor liver transplantatio
Not Applicable
- Conditions
- Health Condition 1: K746- Other and unspecified cirrhosis ofliver
- Registration Number
- CTRI/2020/02/023273
- Lead Sponsor
- Institute of Liver and Biliary Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Portal Venous Pressure (PVP) > 15 mm Hg after reperfusion or
Portal venous flow (PVF) > 250 ml/min/100 gr of liver after reperfusion or
HVPG > 15 mm Hg after reperfusion
Exclusion Criteria
Significant peripancreatic collaterals preventing safe access to splenic artery
Acute Liver Failure as an indication for transplant
ABO incompatible transplants
Pediatric transplants
Refusal to participate in the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the incidence of early graft dysfunction and time to normalization of bilirubin, INR and ascites between the two groups (who undergo graft inflow modulation and those who do not) <br/ ><br>- Group A â?? those who undergo GIM <br/ ><br>- Group B â?? those who do not undergo GIM <br/ ><br>Timepoint: Till patient is dicharged from hospital <br/ ><br>
- Secondary Outcome Measures
Name Time Method - To compare Morbidity and Mortality <br/ ><br>- To compare ICU and total hospital stay <br/ ><br>Timepoint: Till patient is dicharged from hospital