Influence of Wet Clothing on Thermal Protection
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Core Temperature
研究概览
简要总结
The aim of this investigation is to provide guidance for assessing the influence of wet clothing, and its drying time, on body temperature responses during cold air exposure. Twelve healthy and fit adults (men and women aged 18-49) will complete this study. Four cold air exposures (41°F, 180 min) will be randomly conducted, each while wearing a different clothing ensemble that has been saturated by water. During each cold air exposure, you will be asked to rest for 60 min and perform weighted (38.5lbs) treadmill walking for up to 120 min.
详细描述
Participants, in their first visit, will undergo baseline weighted treadmill walking consisting of ~20 min of treadmill walking with a load of 77lbs followed by ~25 min of treadmill walking with a load of 38.5lbs. They will also have their body composition evaluated (DEXA) and be fit for each uniform ensemble. This first laboratory visit will require ~3 hrs.
On separate days, participants will complete 4 experimental trials. After being submerged up to the neck in warm water for two minutes, three of the trials will ask that the participant move to a 41°F air environment, stand with minimal movement for 60 min, complete 60 min of weighted (38.5lb) treadmill walking at 2 mph, and up to 4% grade, and then complete 60 min of weighted (38.5lb) treadmill walking at 2.5 mph and up to 4% grade. Each of these three experimental trial visits will require ~5 hrs.
A single trial will ask that after being saturated in warm water, participants enter a 41°F air environment, immediately begin weighted treadmill walking (38.5lbs) at 2.0mph and up to 4% grade for a duration of 60 min before standing with minimal movement for 60 min. This trial will require ~4 hrs.
During all experimental trials, the primary outcomes include core temperature, measured continuously using a small pill inserted as a rectal suppository, and skin temperature, measured continuously using 11 small skin attached sensors. Secondary outcomes include metabolic rate, heart rate, thermal perceptions, and changes in body mass.
Non-federally employed civilians may be eligible to be paid $13.50/hour for participation (for a total of up to $310).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 49 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Military or civilian, male or female, between the ages of 18 (17 if active duty military) and 49 years.
- •Able to carry a rucksack weighing 35 kg (77lbs) for at least 20 minutes and able to carry a rucksack weighing 17.5kg (38.5lbs) for up to 120 minutes
- •In good health as determined by our OMSO (Office of Medical Support and Oversight) General Medical Clearance.
- •Vaccinated against COVID
- •Willing to refrain from heavy exercise and alcoholic beverages for 24 hours before each testing session.
- •Willing to refrain from smoking or tobacco use for 8 hours before each testing session.
- •Willing to refrain from caffeine ingestion for 12 hours before each testing session.
- •Body fat percentage <18% for males, < 24% for females, once 6 individuals of higher body fat (18% or greater for males, 24% or greater for females) have completed the study.
排除标准
- •History of cold injuries.
- •Raynaud's syndrome.
- •Cold-induced asthma/bronchospasm.
- •Medications or dietary supplements that could alter cardiovascular, thermoregulatory, or vascular control.
- •Heart, lung, kidney, muscle, or nerve disorder(s).
- •Planned MRI during or within two days after completing the study.
- •Known allergy to adhesives.
- •Female and pregnant, planning to become pregnant, or breastfeeding.
结局指标
主要结局
Core Temperature
时间窗: 5 hours
Core temperature will be measured using a temperature pill that is inserted as a rectal suppository.
Skin Temperature
时间窗: 5 hours
Skin temperature will be measured using 11 different skin-attached temperature sensors.
次要结局
- Perceived Skin Wetness(multiple 1 minute collections up to 1 hour)
- Thermal Comfort(multiple 1 minute collections up to 1 hour)
- Thermal Sensation (whole body, feet, and hands)(multiple 1 minute collections up to 1 hour)
- Heart Rate(5 hours)
- Oxygen Consumption/Metabolic Heat Production (MHP)(multiple 5 minute collections up to 1 hour)