To find the add-on effect of Drakshaadi Avaleha and Gandhakadi Yoga tablets in reducing the frequency of blood transfusions in children with Thalassemia Major.
Phase 2
- Conditions
- Health Condition 1: D561- Beta thalassemia
- Registration Number
- CTRI/2023/02/050031
- Lead Sponsor
- All India Institute Of Ayurveda
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Hb electrophoresis diagnosed cases of Thalassemia major.
Parents/guardian willing to give consent to participate in the study.
Exclusion Criteria
Cases having HIV, HBV infection, Hepatic failure, DM, TB, malarial infection, active liver disease etc.
Other haemoglobinopathies like sickle cell anaemia, hereditary spherocytosis etc.
Patients having cardiac and kidney complications.
Patients undergone Splenectomy and allogeneic bone marrow transplantation.
Known allergy to any content of Drakshadi Avaleha and Gandhakadi Yoga.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reduction in blood transfusion frequency.Timepoint: 0 day, after completion of treatment i.e 3 months and during follow up
- Secondary Outcome Measures
Name Time Method 1.Improvement in overall haematocrit value. <br/ ><br>2.Reduction in serum ferritin levels. <br/ ><br>3.Improvement in quality of life assessed through TranQol scale. <br/ ><br>Timepoint: 0 day, after completion of treatment i.e 3 months and during follow up