Comparative Effect of Peppermint Inhalation and Swedish Massage on Chemotherapy Induced-Nausea and Vomiting in Children With Leukemia.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 75
- 试验地点
- 1
- 主要终点
- Frequency of anticipatory vomiting
研究概览
简要总结
Clinical trials was used to compare the effect of peppermint inhalation and Swedish massage on chemotherapy induced-nausea and vomiting in children with leukemia. the main research hypotheses are:
- Children with leukemia who receive peppermint inhalation exhibit less chemotherapy induced- nausea and vomiting than those who don't receive.
- Children with leukemia who receive Swedish massage exhibit less chemotherapy induced-nausea and vomiting than those who don't receive.
- Children with leukemia who receive Swedish massage exhibit less chemotherapy induced- nausea and vomiting than those who receive peppermint inhalation. children divided into three groups of study ( control group, peppermint inhalation group and Swedish massage group) to identify its effect on chemotherapy induced nausea and vomiting.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 6 Years 至 15 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Received first chemotherapy session
- •Intact skin in the massage
排除标准
- •Chronic and acute disorders such as respiratory, cardiovascular diseases...etc.
- •Allergy from any essential oils.
结局指标
主要结局
Frequency of anticipatory vomiting
时间窗: assessed immediately before chemotherapy administration for three consecutive chemotherapy sessions
once/ twice/ three times and more.
Experience of acute nausea .
时间窗: First 24 hours after first chemotherapy administration of study. Assessed within the first 24 hours after second chemotherapy administration of study. Assessed within the first 24 hours after third chemotherapy administration of study.
Yes/no.
Duration of acute nausea .
时间窗: Frst 24 hours after first chemotherapy administration of study. Assessed within the first 24 hours after second chemotherapy administration of study. Assessed within the first 24 hours after third chemotherapy administration of study.
/hours.
Amount of acute vomiting.
时间窗: First 24 hours after first chemotherapy administration of study. Assessed within the first 24 hours after second chemotherapy administration of study. Assessed within the first 24 hours after third chemotherapy administration of study.
Small/ Moderate/ large
Experience of delayed nausea.
时间窗: On second and third days after first chemotherapy administration.On second and third days after second chemotherapy administration. On second and third days after third chemotherapy administration.
Yes/ No.
Amount of delayed vomiting.
时间窗: On second and third days after first chemotherapy administration.On second and third days after second chemotherapy administration. On second and third days after third chemotherapy administration.
Small/ Moderate/ large
Experience of anticipatory nausea
时间窗: assessed immediately before chemotherapy administration for three consecutive chemotherapy sessions
Yes/No
Frequency of anticipatory nausea
时间窗: assessed immediately before chemotherapy administration for three consecutive chemotherapy sessions
once/twice/ three times and more
Frequency of acute nausea .
时间窗: First 24 hours after first chemotherapy administration of study. Assessed within the first 24 hours after second chemotherapy administration of study. Assessed within the first 24 hours after third chemotherapy administration of study.
once/ twice/ three times and more.
Frequency of acute vomiting.
时间窗: First 24 hours after first chemotherapy administration of study. Assessed within the first 24 hours after second chemotherapy administration of study. Assessed within the first 24 hours after third chemotherapy administration of study.
once/ twice/ three times and more.
Duration of anticipatory nausea
时间窗: assessed immediately before chemotherapy administration for three consecutive chemotherapy sessions
/Minutes
Experience of anticipatory vomiting
时间窗: assessed immediately before chemotherapy administration for three consecutive chemotherapy sessions
Yes/No
Worst of anticipatory nausea
时间窗: assessed immediately before chemotherapy administration for three consecutive chemotherapy sessions
No/Mild/Moderate/severe/intolerable
Worst of anticipatory vomiting
时间窗: assessed immediately before chemotherapy administration for three consecutive chemotherapy sessions
No/Mild/Moderate/severe/intolerable
Amount of anticipatory vomiting
时间窗: assessed immediately before chemotherapy administration for three consecutive chemotherapy sessions
Small/ Moderate/ Large
Worst of acute nausea .
时间窗: First 24 hours after first chemotherapy administration of study. Assessed within the first 24 hours after second chemotherapy administration of study. Assessed within the first 24 hours after third chemotherapy administration of study.
No/Mild/Moderate/severe/intolerable
Experience of acute vomiting.
时间窗: First 24 hours after first chemotherapy administration of study. Assessed within the first 24 hours after second chemotherapy administration of study. Assessed within the first 24 hours after third chemotherapy administration of study.
Yes/No.
Worst of acute vomiting.
时间窗: First 24 hours after first chemotherapy administration of study. Assessed within the first 24 hours after second chemotherapy administration of study. Assessed within the first 24 hours after third chemotherapy administration of study.
No/Mild/Moderate/severe/intolerable
Experience of delayed vomiting.
时间窗: On second and third days after first chemotherapy administration.On second and third days after second chemotherapy administration. On second and third days after third chemotherapy administration.
Yes/ No.
Worst of delayed vomiting.
时间窗: On second and third days after first chemotherapy administration.On second and third days after second chemotherapy administration. On second and third days after third chemotherapy administration.
No/Mild/Moderate/severe/intolerable
Worst of delayed nausea.
时间窗: On second and third days after first chemotherapy administration.On second and third days after second chemotherapy administration. On second and third days after third chemotherapy administration.
No/Mild/Moderate/severe/intolerable
Duration of delayed nausea.
时间窗: On second and third days after first chemotherapy administration.On second and third days after second chemotherapy administration. On second and third days after third chemotherapy administration.
/hours.
Frequency of delayed nausea.
时间窗: On second and third days after first chemotherapy administration.On second and third days after second chemotherapy administration. On second and third days after third chemotherapy administration.
once/ twice/ three times and more.
Frequency of delayed vomiting.
时间窗: On second and third days after first chemotherapy administration.On second and third days after second chemotherapy administration. On second and third days after third chemotherapy administration.
once/ twice/ three times and more.
次要结局
未报告次要终点