PERformance of Multi-Cancer Early-detectIon Based on Various Biomarkers in fEmale Cancers, PERCEIVE-II
Recruiting
- Conditions
- Gynecologic Cancer
- Registration Number
- NCT06001099
- Lead Sponsor
- Fudan University
- Brief Summary
This study is a prospective study aimed to validate the performance of combined multi-omitcs assays for early detection of gynecologic cancers. Biomarkers of cfDNA methylation, ctDNA mutation and blood miRNA markers will be evaluated. The study will enroll approximately 2935 female participants, including participants with gynecologic cancers patients and healthy participants.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- Female
- Target Recruitment
- 2935
Inclusion Criteria
Not provided
Exclusion Criteria
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To validate the sensitivity, specificity and accuracy of tissue traceability of an early detection model based on combined cfDNA methylation and serum tumor markers in patients with gynecological malignancies 24 months
- Secondary Outcome Measures
Name Time Method To verify the sensitivity and specificity of serum tumor markers alone as an early detection model for gynecological malignant tumors 24months To verify the sensitivity, specificity and tissue traceability accuracy of cfDNA methylation as an early detection model for gynecological malignancies. 24months
Trial Locations
- Locations (1)
Fudan university shanghai cancer center, Deparment of gynecologic oncology
🇨🇳Shanghai, Shanghai, China