Effect of Aquatic Therapy on Pulmonary Functions in Patients With Muscular Dystrophy
试验速览
- 阶段
- 不适用
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Forced Vital Capacity (FVC)
研究概览
简要总结
This study aimed to assess the efficacy of aquatic therapy on pulmonary functions in patients with muscular dystrophy.
详细描述
Muscular dystrophy (MD) is a group of muscle diseases that results in increasing weakening and breakdown of skeletal muscles over time. The disorders differ in which muscles are primarily affected, the degree of weakness, how fast they worsen, and when symptoms begin. Many people will eventually become unable to walk. Some types are also associated with problems in other organs. The muscular dystrophy group contains thirty different genetic disorders that are usually classified into nine main categories or types.
The signs and symptoms consistent with muscular dystrophy are: progressive muscular wasting, poor balance, scoliosis (curvature of the spine and the back), progressive inability to walk, waddling gait, Calf deformation, Limited range of movement,respiratory difficulty, cardiomyopathy and muscle spasms
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
盲法说明
Blinding process to participants and care providers was impossible because of intervention therapy. We analyzed data by an impartial statistician (outcomes assessor), referring to each arm with an encoded name: Group A (study group) and Group B (control group).
入排标准
- 年龄范围
- 4 Years 至 40 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Their age will ranging from four to forty years.
- •Patients participated in this study will from both sexes.
- •All patients will able to walk supported or unsupported by the therapist.
- •All patients will able to follow the instructions during testing and training.
- •All patients had no fixed contractures or deformities at the lower limb.
排除标准
- •Patients with visual or auditory problems.
- •Patients with structural joints deformities of the lower limbs.
- •Patients with convulsions and fixed contractures.
- •Uncooperative Patient.
结局指标
主要结局
Forced Vital Capacity (FVC)
时间窗: Forced Vital Capacity (FVC) will be assessed at day 90.
Forced vital capacity (FVC) is the amount of air that can be forcibly exhaled from your lungs after taking the deepest breath possible, as measured by spirometry.
Forced Expiratory Volume (FEV1)
时间窗: Forced Expiratory Volume (FEV1) will be assessed at day 90.
Forced expiratory volume in one second (FEV1) is a measurement of your ability to expel air from your lungs. More specifically, and as its name suggests, it is the amount that is exhaled in the first second of purposefully trying to breathe out as much air as possible.
Forced Expiratory Volume/Forced Vital Capacity Ratio (FEV1/FVC ratio)
时间窗: Forced Expiratory Volume/Forced Vital Capacity Ratio (FEV1/FVC ratio) will be assessed at day 90.
is a calculated ratio used in the diagnosis of obstructive and restrictive lung disease.\[2\]\[3\] It represents the proportion of a person's vital capacity that they are able to expire in the first second of forced expiration (FEV1) to the full, forced vital capacity (FVC).\[4\] The result of this ratio is expressed as FEV1%. Normal values are approximately 75%.\[5\] Predicted normal values can be calculated online and depend on age, sex, height, and ethnicity as well as the research study that they are based upon. A derived value of FEV1% is FEV1% predicted, which is defined as FEV1% of the patient divided by the average FEV1% in the population for any person of similar age, sex, and body composition.
次要结局
未报告次要终点
研究者
Mohammed E. Ali, Ph. D Candidate.
Principal Investigator
South Valley University