Effects of antibiotic prophylaxis in dental implant surgery for adult patients: Randomized controlled clinical trial.

Phase 4

Not yet recruiting

• Conditions: Edentulous; Dental Implant Failure; Oral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colon; Surgery - Other surgery

• Registration Number: ACTRN12624001151527
• Lead Sponsor: Master in Oral Surgery and Implantology, University of Granada

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2024-09-23
• Last Update Posted: 30 September 2024

Recruitment & Eligibility

• Status: Not yet recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Patients 18 years and over• Subjects treated periodontally, if necessary, prior to placementof implants• Presence of sufficient bone and soft tissue that does not imply augmentation surgery in the moment of implant placement• Implants placed in a single surgical field

Exclusion Criteria

Patients who, due to their medical condition, require antibiotic prophylaxispostoperative (risk of endocarditis)• Patients undergoing head and neck radiotherapy less than 2 years ago• Diabetics (controlled and uncontrolled)• Allergic to penicillin• Patients treated with antiresorptive drugs• Pregnant or breastfeeding• Immunocompromised• Patients who are taking antibiotics for other reasons• Implants that require simultaneous bone regeneration• Implants in which immediate loading is carried out• Immediate implants

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Early implant failure[Defined by removal of the implant before prosthetic loading. <br>Patient clinic review at 7 days, 14 days, 30 days and 90 days. If early implant failure occurs outside of these periods, the patient will go to the faculty's operating room. Baseline, 7 days, 14 days, 30 days, 90 days<br>]

Secondary Outcome Measures

Name	Time	Method
Presence of postoperatory infection [Postoperative pain and inflammation were evaluated daily on days 1 to 7 post-surgery using a VAS (0= no pain/swelling to 10=maximum imaginable pain/swelling), also recording the amount of anti-inflammatory/analgesic rescue medication taken each day. Presence of infection in the next control appointment (14 days, 30 days, 90 days). Baseline, days 1-7, 14 days, 30 days, 90 days post-surgery. ];Implant stability quotient (ISQ) values for primary and secondary implant stability[ISQ measured on the surgery day, and in day 90. baseline (surgery day) and 90 days post-surgery]