Multi-mOnth Refill of Anti-TB Drugs (MORAD) study in rural eastern Uganda
Phase 3
- Conditions
- Tuberculosis
- Registration Number
- PACTR202403586718783
- Lead Sponsor
- niversity of California Berkeley
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 260
Inclusion Criteria
Aim 1:
1) TB focal persons with =1 year of work experience;
2) Other stakeholders with =3 years of work experience in TB;
3) People with TB on treatment for =4 months including the respective treatment supporters.
Aim 2
People with drug-susceptible PTB =15 years.
Exclusion Criteria
Aim 1
1) Unreachable participants
Aim 2:
1) People with TB who are very ill and require close clinical and laboratory monitoring or hospitalization;
2) People with PTB likely to migrate to another district/ or place during the study period;
3) Treated with anti-TB drugs for =2 months;
4) People with drug-resistant TB;
5) People with extrapulmonary TB since treatment duration exceeds 6 months.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Treatment success measured at 6 months following TB treatment.
- Secondary Outcome Measures
Name Time Method Sputum smear conversion measured at 2 months following TB treatment initiation among people with bacteriologically confirmed pulmonary TB.;Sputum smear conversion measured at 5 months following TB treatment initiation among people with bacteriologically confirmed pulmonary TB.