NCT01039714Unknown不适用
Preoperative Vitamin D Levels as a Prognostic Factor for Postoperative Hypocalcemia and Hypoparathyroidism After Total Thyroidectomy
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Impact of preoperative vitamin D levels on postoperative hypocalcemia after total thyroidectomy.
研究概览
简要总结
Hypocalcemia is one of the most frequent complications of total thyroidectomy, a procedure used for benign as well as malignant conditions of the thyroid gland. Postoperative hypocalcemia is usually caused by hypoparathyroidism. Vitamin D is implicated in calcium metabolism as it increases intestinal calcium transport and regulates parathormone production. Aim of the present study is to evaluate preoperative vitamin D levels as a prognostic factor for postoperative hypocalcemia and hypoparathyroidism.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient is over 18 years old
- •Patient scheduled for total thyroidectomy
- •Patient signs and dates a written informed consent form (ICF) and indicates an understanding of the study procedures
排除标准
- •Primary hyperparathyroidism
- •Primary hypoparathyroidism
- •Chronic Renal Failure
- •Hypoalbuminemia
- •Neck irradiation
- •Systematic Diseases (e.g., infections)
- •Thyroid or parathyroid cancer
- •Osteoporosis
- •Drugs that influence calcium metabolism (vitamin D analogues, oral calcium supplements, biphosphonates, teriparatide, thiazide diuretics)
结局指标
主要结局
Impact of preoperative vitamin D levels on postoperative hypocalcemia after total thyroidectomy.
时间窗: 24 hours postoperatively
次要结局
- Impact of preoperative vitamin D levels on parathyroid function after total thyroidectomy.(24 hours postoperatively)
研究者
研究点 (1)
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