Prevalence of Subclinical Atrial Fibrillation in High Risk Heart Failure Patients and Its Temporal Relationship With Hospital Readmission for Heart Failure
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 242
- 试验地点
- 5
- 主要终点
- Subclinical atrial fibrillation ≥30 minutes in duration
研究概览
简要总结
Multicentre, prospective cohort study in patients with a history of HF with preserved or reduced ejection fraction admitted to hospital with acutely decompensated HF. Eligible and consenting patients will be enrolled at 3 Hamilton, Ontario area hospitals and receive 28-day ECG monitoring implemented at the time of hospital discharge. Patients will be followed for a total of 1 year from hospital discharge.
详细描述
In patients discharged from hospital after an admission for acute heart failure (HF) decompensation, subclinical atrial fibrillation (AF) of 30 minutes or greater in duration is common (at least 15% of patients without prior AF) and is associated with increased risk of re-hospitalization within 30-days.
Study Objectives:
- To evaluate the prevalence of subclinical AF ≥30 minutes in duration in patients discharged from hospital following an admission for acute HF exacerbation and who have no known history of clinical AF.
- To examine the temporal association between subclinical AF ≥30 minutes in duration and 30-day hospital readmission for HF.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Hospitalized with a most responsible diagnosis of acute decompensated heart failure.
- •Clinical signs and symptoms of heart failure as per the Boston criteria (i.e. score ≥8)
排除标准
- •History of clinical atrial fibrillation
- •History of hypertrophic cardiomyopathy or congenital heart disease.
- •End stage renal disease or advanced renal dysfunction (e.g. estimated glomerular filtration rate, eGFR < 15 mL/min/1.73 m2)
- •Cardiothoracic surgery in the past 30 days or imminently planned (does not include percutaneous procedures).
- •Unable or unwilling to provide informed consent.
- •Presence of a pacemaker or an ICD with an atrial lead (which can already diagnose AF).
结局指标
主要结局
Subclinical atrial fibrillation ≥30 minutes in duration
时间窗: 30 days post-discharge
次要结局
- Heart failure re-hospitalization(30 days post-discharge)