NCT01847248已完成不适用
HSPA12B as a Potential Biomarker for Sepsis and Severe Sepsis
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 118
- 试验地点
- 1
- 主要终点
- 28-day mortality
研究概览
简要总结
- Molecules indicating endothelial injury may serve as biomarkers for severe sepsis because of the critical role of endothelial injury in organ dysfunction during severe sepsis.
- HSPA12B is primarily located in endothelial cells and detectable during sepsis.
- The investigators speculated that HSPA12B from endothelial cells might be correlated with severe sepsis.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Adult patients
- •Patients meet the diagnostic criteria according to the grouping
排除标准
- •patients without informed consent
- •patients who were undergoing continuous renal replacement therapy before sampling
- •patients with special infection induced by virus, tubercle bacillus, mycoplasma, Chlamydia, and so on
结局指标
主要结局
28-day mortality
时间窗: 28 days
mortality within 28 days after recruitment.
次要结局
未报告次要终点
研究者
研究点 (1)
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