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Clinical Trials/NCT01847248
NCT01847248
Completed
Not Applicable

HSPA12B as a Potential Biomarker for Sepsis and Severe Sepsis

Changhai Hospital1 site in 1 country118 target enrollmentMay 2011
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ConditionsSepsis

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Sepsis
Sponsor
Changhai Hospital
Enrollment
118
Locations
1
Primary Endpoint
28-day mortality
Status
Completed
Last Updated
12 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

  • Molecules indicating endothelial injury may serve as biomarkers for severe sepsis because of the critical role of endothelial injury in organ dysfunction during severe sepsis.
  • HSPA12B is primarily located in endothelial cells and detectable during sepsis.
  • The investigators speculated that HSPA12B from endothelial cells might be correlated with severe sepsis.
Registry
clinicaltrials.gov
Start Date
May 2011
End Date
October 2013
Last Updated
12 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Jia-feng Wang

Dr.

Changhai Hospital

Eligibility Criteria

Inclusion Criteria

  • •Adult patients
  • •Patients meet the diagnostic criteria according to the grouping

Exclusion Criteria

  • •patients without informed consent
  • •patients who were undergoing continuous renal replacement therapy before sampling
  • •patients with special infection induced by virus, tubercle bacillus, mycoplasma, Chlamydia, and so on

Outcomes

Primary Outcomes

28-day mortality

Time Frame: 28 days

mortality within 28 days after recruitment.

Study Sites (1)

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