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临床试验/CTRI/2024/07/070071
CTRI/2024/07/070071尚未招募不适用

Effect of Optic Nerve Sheath Diameter in Paediatric patients undergoing laparoscopic surgeries

Bangalore Medical College and Research Institute1 个研究点 分布在 1 个国家目标入组 23 人开始时间: 2024年7月21日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
23
试验地点
1
主要终点
To study the impact of ONSD in laparoscopic surgeries during general anaesthesia

研究概览

简要总结

In laparoscopic surgeries carbon dioxide and pneumoperitoneum result in various events such as the potential to increase cerebral blood flow, intracranial pressure and intraocular pressure. Pneumoperitoneum elevates ICP because of the increased abdominal pressure and ICP increases even further in the Trendelenberg position. Pneumoperitoneum also increases cerebral blood flow resulting in an acute rise in ICP that may be harmful to patients with head injury or unrecognized intracranial mass lesion. Direct ICP measurement using a small pressure sensitive probe inserted through the skull is the gold standard for monitoring ICP. For routine surgeries the risks of such an invasive test outweigh the benefits. A new non invasive method the Optic Nerve Sheath Diameter(ONSD) measurement via ultrasonography detects the raised ICP and is reliable and inexpensive and can be repeated many a time. Due to elastic subarachnoid trabecular anatomy, the optic nerve sheath is most distensible at 3mm behind the globe thus making it the best point for ONSD interpretation. ONSD was reported to increase between 15 and 30 mm Hg. Ultrasound based ONSD measurement have been extensively used quickly and non invasively to assess ICP  both at clinical and research levels. Hence our study aimed to measure ONSD to assess ICP in paediatric patient

研究设计

研究类型
Observational

入排标准

年龄范围
6.00 Year(s) 至 16.00 Year(s)(—)
性别
All

入选标准

  • ASA Grade I AND Grade II Children undergoing laparoscopic surgeries.

排除标准

  • Children with a history of allergy to local anesthetic Children with bleeding disorder Evidence of peritonitis or septicemia Presence of hyperthyroidism Neuritis Glaucoma Orbital fracture Patients refusal.

结局指标

主要结局

To study the impact of ONSD in laparoscopic surgeries during general anaesthesia

时间窗: To measure ONSD 15 minutes of pneumoperitoneum and 15 minutes post pneumoperitoneum

次要结局

  • Impact on ICP(To measure ONSD 15 minutes of pneumoperitoneum & 15 minutes post pneumoperitoneum)

研究者

发起方
Bangalore Medical College and Research Institute
申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Dr Akshay B

Bangalore Medical College and Research Institute

研究点 (1)

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