Community Epidemiology and Typology of Third-generation Cephalosporins Resistant Enterobacteriaceae (Prevalence, Resistance Mechanisms and Risk Factors) in Reunion Island
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- Digestive prevalence rate of 3GCREB
研究概览
简要总结
In its report dated april 2014, World Health Organization confirms antibiotic resistance dissemination in all parts of the world, in hospitals and in community and worries about a possible comeback to a pre-antibiotic era during the 21st century. For the last 15 years, third-generation cephalosporins resistant enterobacteriaceae (3GCREB) prevalence is continuously increasing. Community 3GCREB prevalence has not been studied whereas several observations made in Reunion Island hospital suggest a diffusion in community. In this situation of world-wide and regional extension of bacterial resistance, the investigator offers to study bacterial resistance to antibiotic in Reunion Island community.
详细描述
The investigator is focused on E. coli species exhibiting BLSE or metallo-betalactamases production that could be encountered du to the increasing level of migratory flow in Reunion Island.
Fecal sample collection will be used for further investigations on bacterial typology.
研究设计
- 研究类型
- Observational
- 观察模型
- Ecologic Or Community
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •aged over 18 years old
- •admitted in emergency ward or intensive care of the university hospital of Reunion Island
- •who received the patient information notice and who gave their consent
- •who have a stool sample performed in the 48 hours following admission
- •who understand and can read French
排除标准
- •transferred from a short-term, middle-term or long-term stay health facility
- •who have a stool sample performed more than 48 hours following admission.
结局指标
主要结局
Digestive prevalence rate of 3GCREB
时间窗: through study completion, an average of 1 day
estimate of digestive prevalence rate of 3GCREB in participating patients and extrapolation to Reunion Island community population.
次要结局
未报告次要终点