Prognostic Impact of PMI in Stable CAD Undergoing PCI
- Conditions
- Periprocedural Myocardial InjuryCoronary Artery DiseasePercutaneous Coronary Intervention
- Registration Number
- NCT04239404
- Lead Sponsor
- Shanghai Zhongshan Hospital
- Brief Summary
This is a single-center, observational, prospective study. This study aims to observe the effect of periprocedural myocardial injury on cardiovascular events in patients undergoing elective percutaneous coronary intervention, and to detect the levels of serum inflammatory factors before and after intervention to predict the occurrence of periprocedural myocardial injury and its association with cardiovascular events.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 2000
Inclusion Criteria
- underwent elective coronary stenting
- patients permit informed consents
Exclusion Criteria
- acute STEMI
- NYHA class III-IV heart failure
- moderate-to-severe valvular disease
- missing post-PCI troponin results
- active infection, respiratory failure
- liver dysfunction (liver enzyme >3xURL or bilirubin >2xURL),
- malignancy and systemic connective tissue disease
- unable to get a informed consents
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Major cardiac events 12 months after PCI cardiac death, target vessel revascularization, target lesion revascularization, non-fatal myocardial infarction, heart failure, angina pectoris
- Secondary Outcome Measures
Name Time Method Serum level of inflammatory factors 1 day after PCI Serum level of inflammatory factors including TNFα, IL-6 and so on.
Trial Locations
- Locations (1)
180 Fenglin Road
🇨🇳Shanghai, Shanghai, China