Theory of Mind, Empathy and Eye Gaze Strategies During an Artwork Observation in Neurodegenerative Pathologies.
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 70
- Locations
- 2
- Primary Endpoint
- 1. Gaze patterns
Study Overview
Brief Summary
Analysis of gaze patterns during social cognition tasks and standardised exploration of a specific artwork, between elderly subjects without cognitive disorders and subjects with neurodegenerative diseases such as Fronto-Temporal Dementia, Alzheimer's Dementia or Parkinson's Disease
Study Design
- Study Type
- Interventional
- Allocation
- Non Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Other
- Masking
- None
Eligibility Criteria
- Ages
- 60 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Male or Female.
- •60 years old and above.
- •Sufficient written and oral expression in French.
- •Benefit from French or Monaco Social security.
- •Written informed consent signed by the patient.
- •For the control group: voluntary subjects, without cognitive impairment.
- •For the FTD / AD / PD groups: patients diagnosed with one of these diseases, and volunteers to participate in the study.
Exclusion Criteria
- •General anaesthesia within 3 months.
- •Ophthalmological problems preventing a video-oculography examination.
- •Oculomotor disorders such as "fixation disorders" or "ocular tracking disorders".
- •History of stroke.
- •Cognitive disorders of the type: visual agnosia, visuo-spatial disorder, visuo-perceptual disorder or aphasia.
Outcomes
Primary Outcomes
1. Gaze patterns
Time Frame: baseline
Comparison of gaze patterns between the control group and the pathological groups, during standardized exploration of a specific artwork. Evaluation criteria: difference in the number of fixation
2.Gaze Patterns
Time Frame: Baseline
Comparison of gaze patterns between the control group and the pathological groups, during standardized exploration of a specific artwork. Evaluation criteria: difference in exploration strategy (chronology) on target areas.
3.Gaze Patterns
Time Frame: Baseline
Comparison of gaze patterns between the control group and the pathological groups, during standardized exploration of a specific artwork. Evaluation criteria: difference in time spent on target areas.
Secondary Outcomes
- Cognitive Theory of mind during an artwork observation: Score 1(Baseline)
- Affective empathy: Score 4.(Baseline)
- Affective empathy: The Empathy Quotient (EQ).(Baseline)
- Cognitive Theory of mind during an artwork observation: Score 2(Baseline)
- Affective ToM : The Reading the Mind in the Eye test - RME - (Baron-Cohen S at al., 2001)(Baseline)
- Cognitive Theory of mind: TOM-15 a false-belief task to assess cognitive theory of mind(Baseline)
- Affective ToM (Score 3)(Baseline)