Effects of Manual Therapy Versus Therapeutic Exercise on Knee Osteoarthritis: A Randomized Control Trial
试验速览
- 阶段
- 2 期
- 状态
- 终止
- 入组人数
- 1
- 试验地点
- 2
- 主要终点
- Suprapatellar effusion measured via diagnostic ultrasound
研究概览
简要总结
Earlier research has shown that exercising while receiving manual therapy improves function and reduces pain in people with knee osteoarthritis. However, very little is known about the mechanisms by which manual therapy and exercise reduce pain and improve function. This study will ask subjects with knee osteoarthritis to receive one of the following interventions: (1) no treatment, (2) exercise only, or (3) manual therapy only. Measures will be taken of the patient's knee range of motion, knee swelling and pain before and after receiving the intervention. These measures will be analyzed to determine what effect exercise and manual therapy applied to the knee have on improving knee range of motion and reducing knee pain and swelling. Swelling will be measured using an ultrasound device which is used to take pictures inside the knee. This type of ultrasound measurement is painless and harmless.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 89 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Diagnosis of knee osteoarthritis.
排除标准
- •Inability to ambulate at least 100 feet, ride a stationary bicycle for at least 10 minutes, or lie in the prone position for at least 10 minutes,
- •Intra-articular knee injection within one month of study inception,
- •A history of exercise induced or uncontrolled angina within three months of the study entry,
- •Severe dyspnea at rest,
- •Previous bilateral total knee arthroplasty,
- •Pregnancy, OR
- •The absence of knee pain at the time of recruitment for the study.
结局指标
主要结局
Suprapatellar effusion measured via diagnostic ultrasound
时间窗: Outcome measure will be measured 1 minute prior to intervention and 1 minute after intervention.
次要结局
- Pain Visual Analog Scale(Outcome measure will be measured 3 minutes prior to intervention and 3 minutes after intervention.)
- Goniometric knee arc range of motion(Outcome measure will be measured 5 minutes prior to intervention and 5 minutes after intervention.)
- Western Ontario and McMaster Universities Index of osteoarthritis of the knee(Outcome measure will be measured 12 minutes prior to intervention and 7 minutes after intervention.)