Study of the Prevalence and Patterns of Drug Resistance of Mycobacterium Tuberculosis Using GeneXpert (MTB/RIF) and Xpert (MTB/XDR) Assays
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Sohag University
- Enrollment
- 250
- Locations
- 1
- Primary Endpoint
- Detection of number of cases resistant to Rifampicin and other anti- TB drugs
Study Overview
Brief Summary
Tuberculosis is a major cause of ill health and one of the leading causes of death worldwide. Early, rapid and accurate diagnosis of all TB patients and prompt treatment with any form of drug-susceptible or drug resistant TB is fundamental. Identifying the pattern of drug resistance will ensure that the most effective therapy can be selected. The aim of this study is to assess the prevalence and patterns of drug resistance of mycobacterium tuberculosis and to detect the possible risk factors associated with resistant cases.
Study Design
- Study Type
- Observational
- Observational Model
- Case Only
- Time Perspective
- Cross Sectional
Eligibility Criteria
- Ages
- 12 Years to — (Child, Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •geneXpert positive patients in pulmonary and extrapulmonary cases
Exclusion Criteria
- •age below 12 years
Outcomes
Primary Outcomes
Detection of number of cases resistant to Rifampicin and other anti- TB drugs
Time Frame: within 6 months of starting treatment
Using of GeneXpert (MTB/RIF) and Xpert (MTB/XDR) assays to detect resistance to Rifampicin and other anti -TB drugs among TB positive cases
Secondary Outcomes
- Detection of common Risk factors associated with resistant cases(within 6 months of starting treatment coarse)
Investigators
Omnia Abdelazim Mohamed
chest specialist
Sohag University