Safety and efficacy after multiple carbon-ion radiotherapy for patients with hepatocellular carcinoma
Not Applicable
- Conditions
- hepatocellular carcinoma
- Registration Number
- JPRN-UMIN000037241
- Lead Sponsor
- ational Institutes for Quantum and Radiological Science and Technology
- Brief Summary
Delivering re-irradiation for recurrent hepatocellular carcinoma is challenging because of possible risk of radiation induced liver disease. Here, we evaluated the safety and efficacy of repeated hypofractionated carbon-ion radiotherapy in 60 patients of recurrent hepatocellular carcinoma using 2 or 4 fractions.Repeated extremely hypofractionated carbon-ion radiotherapy proved to be safe with promising outcomes in this study.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Not provided
Exclusion Criteria
1.An estimated life expectancy of less than 6 months. 2.Presence of digestive tract within the clinical target volume 3.Medical comorbidities precluding safe administration of re cIRT.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Safety after multiple carbon-ion radiotherapy for liver
- Secondary Outcome Measures
Name Time Method Efficacy after multiple carbon-ion radiotherapy for hepatocellular carcinoma