Effects of metformin at high pressure and mild hypothyroidism
Not Applicable
- Conditions
- Subclinical hypothyroidismE03.9
- Registration Number
- RBR-6crdyx
- Lead Sponsor
- Hospital de Clínicas de Porto Alegre - UFRGS
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruitment completed
- Sex
- Not specified
- Target Recruitment
- Not specified
Inclusion Criteria
Volunteers of both sexes; aged between 18 and 65; with TSH greater than the upper limit of normal for the method in two steps, the first by any method and the second measured by chemiluminescence accompanied by free T4 levels within normal limits.
Exclusion Criteria
Previous diagnosis of type 2 diabetes; use of levothyroxine; contraindications to the use of metformin; known abnormal liver function; heart failure NYHA III-IV despite optimal drug therapy; serious mental illness; any terminally ill; malignancy not cured or in treatment; contrast studies in the last three months; use of medications known to interfere with thyroid function.
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method