NCT05571618进行中（未招募）不适用
A Multicenter, Real-world Study of the Efficacy and Safety of Antibody-drug Conjugates (ADCs) Rechallenge in Patients with Prior Exposure to ADCs Metastatic Breast Cancer
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- PFS
研究概览
简要总结
To investigate the efficacy and safety of ADC rechallenge
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •age > 18 years old.
- •Diagnosed with Metastatic Breast Cancer.
- •Patients with prior exposure to ADC (either in the adjuvant setting or metastatic disease are allowed).
- •Patients plan to or have received ADCs for the second or more time.
- •Complete medical history was available.
排除标准
- •Medical history was incomplete
研究组 & 干预措施
Group1
干预措施: ADC (Drug)
结局指标
主要结局
PFS
时间窗: 6 weeks
Progression free survival
次要结局
- Adverse events(6 weeks)
- DoR(6 weeks)
- ORR(6 weeks)
- OS(6 weeks)
- CBR(6 weeks)
研究者
研究点 (1)
Loading locations...
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