Efficacy of Pidangunari kudineer chooranam for Non_Alcoholic Fatty Liver Disease (NAFLD) among patients attending OPD at Government Siddha medical college Hospital, Chennai_A pilot study
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- To evaluate the efficacy of Pidangunari kudineer chooranam in Non_alcoholic fatty liver disease (NAFLD)by improvement in grades of fatty liver
研究概览
简要总结
Non_alcoholic fatty liver disease(NAFLD) is a spectrum of disease characterized by accumulation of fat or steatosis in liver cells in the absence of other identicable causes such as Alcohol consumption.It includes simple fatty liver, NASH fibrosis and cirrhosis with a complex multi-hit pathophysiology. The initiating events in NAFLD is increased hepatic free fattyacid reflux. The imbalance between the rate of import/synthesis and the rate of export/catabolism of fatty acids in the liver leads to the development of steatosis.so it is considered to evaluate the efficacy of Siddha medicine Pidangunari kudineer chooranam in treating Non-alcoholic fatty liver disease.The study is designed to access the improvement of the patient from grade II to grade I in USG abdomen before and after treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 30.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Subjects having complaints of pain or discomfort in the right upper quadrant/epigastric region of the abdomen, nausea, vomiting, indigestion, anorexia ,fatigue, bloating and distension.
- •Obese subjects.
- •Metabolic syndrome(T2DM,dyslipidaemia).
- •Grade I,II, fatty liver in USG abdomen.
排除标准
- •Patients with Chronic Kidney Disease, Cardiovascular Disease.
- •Patients with known liver diseases such as viral hepatitis, biliary disorder, liver abscess, cirrhosis and malignancy.
- •Patients in vulnerable group such as Pregnancy,lactation.
结局指标
主要结局
To evaluate the efficacy of Pidangunari kudineer chooranam in Non_alcoholic fatty liver disease (NAFLD)by improvement in grades of fatty liver
时间窗: 90 days
次要结局
- Reduction in values of lipid profile and LFT will be assessed before and after Treatment(Improvement in the symptoms of NAFLD before and after treatment.)
研究者
Dr S Kowsalya
Government Siddha Medical College, Chennai