Sonographic Evaluation of Diaphragmatic Function in Critical Care Patients With Use of Non Invasive Ventilation

Completed

• Conditions: Invasive Mechanical Ventilation; Critical Care

• Registration Number: NCT02380547
• Lead Sponsor: University Hospital, Strasbourg, France

Brief Summary

Usefulness of non invasive ventilation in patients extubated after more than 48 hours of invasive ventilation is still in debate except for specific patients (chronic pulmonary disease and chronic heart failure).

Many experimental and clinical studies have shown that diaphragmatic function is depressed by mechanical ventilation in intubated patients.

The investigators will test the hypothesis that non invasive ventilation after extubation may improve diaphragmatic function

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2015-02-23
• Study First Submitted QC: 2015-02-27
• Study First Posted: 2015-03-05
• Study Start: 2015-06-19
• Primary Completion: 2016-07-15
• Study Completion: 2016-07-15
• Status Verified: 2018-03
• Last Update Submitted: 2018-03-21
• Last Update Posted: 2018-03-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

• Patient extubated after at least 48 hours of invasive ventilation
• Requiring non invasive ventilation
• Consent of patient

Exclusion Criteria

• Diaphragmatic paralysis
• Neuromuscular disease
• significant pleural effusion
• atelectasis requiring bronchoscopy
• abdominal hypertension

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Diaphragmatic excursion	After 24 h of NIV use
Diaphragmatic thickening	After 24 h of NIV use

Trial Locations

Locations (1)

Service d'anesthésie- réanimation chirurgicale, Nouvel Hôpital Civil, Hôpitaux Universitaires de Strasbourg; 🇫🇷 Strasbourg, France