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Prospective cohort research for aortic root dilatation and non-elasticity after surgical repair in adults with Tetralogy of Fallot

Not Applicable
Recruiting
Conditions
Tetralogy of Fallot
Registration Number
JPRN-UMIN000017555
Lead Sponsor
Tokyo Metropolitan Children's Medical Center
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
100
Inclusion Criteria

Not provided

Exclusion Criteria

1) Double outlet right ventricle 2) Complicated heart diseases related to aortic dilatation: bicuspid aortic valve, coarctation of aorta, interruption of aorta 3) Complicated connective tissue diseases related to aortic dilatation: Marfan syndrome, Loeys-Dietz syndrome, and others 4) ineligibles for subjects judged by a doctor in attendance

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The pace of aortic root dilatation
Secondary Outcome Measures
NameTimeMethod
1) Incidence of aortic root dilatation 2) Aortic elasticity evaluated by pulse wave velocity 3) Effect of oral medication, especially angiotensin receptor blocker and angiotensin converting enzyme inhibitor
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