Kinetics of Serum β-D-glucan During Peritonitis With Candida in Resuscitation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 70
- 试验地点
- 2
- 主要终点
- Blood determination of serum β-D-glucan kinetics in patients with peritonitis
研究概览
简要总结
Intraabdominal fungal infections with Candida are constantly increasing. Their diagnosis and treatment is difficult. Morbidity and mortality are high. Β-D-Glucan has been proposed as a marker of systemic fungal infection in candidemia. Moreover, its kinetics is associated with therapeutic success. On the other hand, there are no data on intraabdominal infections that are much more frequent. The objective of the study is to evaluate the initial levels of β-D-glucan and its daily kinetics during the treatment of fungal peritonitis in resuscitation compared to a control group with a yeast-free peritonitis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Screening
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Major Patient (age ≥ 18 years)
- •Community or associated peritonitis, operated and hospitalized in resuscitation
- •Affiliation to a social security scheme
排除标准
- •Allergy known to echinocandins
- •Dying Patient
- •Limitation of care
- •Predictable duration of follow-up ≤ 10 days
- •Transfusion within 3 months
- •Patient minor, patient under guardianship or curatorship
结局指标
主要结局
Blood determination of serum β-D-glucan kinetics in patients with peritonitis
时间窗: 28 days
Blood determination of serum β-D-glucan kinetics in patients with peritonitis
次要结局
未报告次要终点