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Clinical Trials/TCTR20210527001
TCTR20210527001
Completed
Phase 4

Effect of age on the median effective dose and 95% effective dose of intravenous fentanyl for blunting the hemodynamic response to tracheal intubation: a double-blind, up-and-down sequential method trial

eurological Institute of Thailand0 sites86 target enrollmentMay 27, 2021
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ConditionsPatients undergoing general anesthesia with endotracheal intubation.Fentanyl, Hemodynamic Response, Tracheal Intubation

Overview

Phase
Phase 4
Intervention
Not specified
Conditions
Patients undergoing general anesthesia with endotracheal intubation.
Sponsor
eurological Institute of Thailand
Enrollment
86
Status
Completed
Last Updated
last year
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
May 27, 2021
End Date
March 31, 2022
Last Updated
last year
Study Type
Interventional
Sex
All

Investigators

Sponsor
eurological Institute of Thailand

Eligibility Criteria

Inclusion Criteria

  • •1\. Age 20 \- 80 years
  • •2\. Undergoing general anesthesia with ETT
  • •3\. Elective surgery
  • •4\. ASA physical status I or II
  • •5\. No history of fentanyl allergy

Exclusion Criteria

  • •1\. In OR, at the time of induction ( BP greater than or equal to 180/110 mmHg)
  • •2\. Expected difficult airway
  • •3\. BMI greater than or equal to 30 kg/m2
  • •4\. Fentanyl was given within 4 hours of admission to the study
  • •5\. Ischemic heart disease, arrhythmia
  • •6\. Increased ICP
  • •7\. Creatinine clearance less than 30 ml/min

Outcomes

Primary Outcomes

Not specified

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