Taipei Tzu Chi Hospital , Buddhist Tzu Chi Medical Foundation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 120
- 主要终点
- The prediction of optimal minute ventilation as successful weaning parameters in patients with prolong mechanical ventilator.
研究概览
简要总结
- purpose of study: optimal minute could be the prediction of successful weaning and become the new weaning parameter.
- study design: inclusion criteria: investigators will perform this study at our respiratory care center. Patients who had been maintained on mechanical ventilator in excess of 3 weeks before respiratory care center admission and all previous weaning attempts had ailed.
Exclusion criteria: Patients do not have spontaneous breath. Terminal cancer stage and unstable hemodynamics condition. 3. study duration: 2016/01/01~12/31
详细描述
Investigators will preform this study at our respiratory care center. Initially, Investigators collected all physiological parameters and baseline characteristics of patients with prolong mechanical ventilator. Investigators use Gold-Galileo ventilator and patients use adaptive support ventilation mode. In adaptive support ventilation, the clinician enters a target minute volume , using a parameter called minute ventilation percentage. The minute ventilation percentage setting be initially set at 100% (the 100%minute ventilation setting), which provides a target minute ventilation of 0.1 L/min/kg of ideal body weight . Investigators observed respiratory frequency of patients, the minute ventilation percentage was increased every 5 min until the mandatory breath began to appear and spontaneous rate is zero. If the minute ventilation percentage had exceeded 250%, but patients do not have mandatory rate appeared, the optimal minute ventilation of the patient is means above 250%. Investigators also measure other weaning parameters. Finally, Investigators analyze the prediction of optimal minute ventilation as a weaning parameter.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients who had been maintained on mechanical ventilation in excess of 3 weeks before respiratory care center admission and all previous weaning attempts had failed.
排除标准
- •Patients do not have spontaneous breath. Patients do not use invasive mechanical ventilator. Terminal cancer stage and hemodynamics unstable.
结局指标
主要结局
The prediction of optimal minute ventilation as successful weaning parameters in patients with prolong mechanical ventilator.
时间窗: 2016/01/01~2016/12/31,1 year
Investigators observed the condition of patients with adaptive spontaneous ventilation mode that the patient admitted to respiratory care center first day
次要结局
未报告次要终点