NCT01989832已完成不适用
Pharmaco-economical Study in Kidney Transplantation
University Hospital, Limoges0 个研究点目标入组 570 人开始时间: 2013年2月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 570
- 主要终点
- Number of Death
研究概览
简要总结
The prevalence of renal acute rejection in transplantation is reduced thanks to the optimized use of immunosuppressive drugs. However, graft survival at ten years has not improved since then; this may be explained in part by the toxicity of these drugs, viral infections, and other comorbidities (diabetes, cardiovascular diseases ...).
According to transplant center, strategies for the combination of immunosuppressive drugs are different, and probably involve a difference in the global cost of patient management. There is no recommendation in France to establish similar practices.
EPHEGREN is an observational, prospective, multicentric, pharmacoeconomic study for the renal transplant patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients in the first month of renal graft, or patients already included in an other epidemiological French study (EPIGREN) in the 0-6 month period
- •Men of women aged more than 18 years
- •Patients able to exercise in writing their informed and free consent to participate to the biological collection
- •Patients not opposing to collect their medical data
- •Patients registered with a social security system
- •Patients able to complete the questionnaires
排除标准
- •Patients aged less than 18 years and patients under guardianship
- •Patients with a follow-up at another center other than those part of the study
结局指标
主要结局
Number of Death
时间窗: 4 years
次要结局
- to examine nature, dose and exposure in immunosuppresseurs.(4 years)
研究者
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